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  • More
    • Home
    • Leadership Team
    • Our Brand Story
      • Our Values
      • Our Vision and Mission
      • Why Axleres
    • Business Models
      • Business Model Overview
      • Project Management
      • Project Execution
      • Custom Models
    • Engagement Models
      • Engagement Overview
      • A Friend In Need
      • On Ground Strike Team
      • A Companion
      • A Technical Quarterback
    • Our Offerings
      • Integrated Drug Discovery
      • Pre Clinical Development
      • Clinical Supplies
      • Commercialization
    • Contact US
  • Home
  • Leadership Team
  • Our Brand Story
    • Our Values
    • Our Vision and Mission
    • Why Axleres
  • Business Models
    • Business Model Overview
    • Project Management
    • Project Execution
    • Custom Models
  • Engagement Models
    • Engagement Overview
    • A Friend In Need
    • On Ground Strike Team
    • A Companion
    • A Technical Quarterback
  • Our Offerings
    • Integrated Drug Discovery
    • Pre Clinical Development
    • Clinical Supplies
    • Commercialization
  • Contact US

Late-Phase Development & Commercialization

Manufacturing and Continuous Supplies

We support programs moving into pivotal trials, validation, and beyond — helping clients prepare for launch and ensure commercial readiness through expert-driven execution and partner coordination. 

Our capabilities include:

Process Validation & PPQ Campaigns

  • Support for commercial process design and scale-up 
  • Preparation and execution of Process Performance Qualification (PPQ) campaigns 
  • Documentation of continued process verification (CPV) strategies 

Regulatory Support for NDA/BLA Filings

  • Late-stage gap analysis and dossier consolidation 
  • Authoring or reviewing CMC sections (NDA, BLA, MAA) including stability, comparability, and control strategies 

Commercial Manufacturing Readiness

  • Supplier/partner qualification, quality agreement support, and technical audits 
  • Dual-site readiness planning and alternate site validation 
  • Operational excellence and lean manufacturing strategy development 

Strategic Partner Transitions or Dual-Source Planning

  • Mid- or late-phase CDMO transitions with minimal program disruption 
  • Support for dual-source validation and technology bridging 
  • Risk mitigation planning for supply continuity 

Lifecycle Management & Market Support

  • Post-approval variation support and regulatory maintenance 
  • Process improvement, yield enhancement, and cost optimization initiatives 
  • Commercial supply chain and logistics oversight (where applicable) 

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